- 2 small avocados, peeled and chopped
- ½ lb. Asparagus tips
- 1 small jicama, peeled and chopped
- 1 pink grapefruit, peeled, seeded, chopped
- 1 cup radish sprouts (or sprouts of your choice)
- Juice of 2 limes
- 2 TBSP chopped lemon balm herb (optional)
- 2 TBSP chopped mint
- 4 TBSP chopped green scallion
- 2 TBSP red onion, minced
- Braggs, Sea Salt or Himalayan Salt to tast
Combine all ingredients except the sprouts. Serve on a bed of lettuce topped with small amount of sprouts. Remove the white pith from the grapefruit for a sweeter tasting dish.
From my friend Rita Romano
Human growth hormone (HGH), is one of the initiators and controllers of physical and psychological processes that happen in our body.
If you’ve listened closely in science and biology class, you’d remember a funny thing about the endocrine system. For those who forgot, the endocrine system is a part of the body (like the neurological system, or digestive system) that is in charge of excreting various hormonal compounds into the body to give other organs the chemicals and signaling they need to work well.
The endocrine system consist of:
- testes or ovaries.
The primary endocrine gland is the pituitary, a small nut-like gland that is nested in the center of our brain, just below the hypothalamus. The role of this gland kind of fits well with the location it is placed – it is the “head” of the endocrine system.
The pituitary gland produces and excretes several different hormones that oversee, or better, initialize and control the production of hormones in other glands in our body. The hormones it produces can stimulate other organs and metabolic processes, and they can induce the production of other hormones which together work for the betterment of our organism.
Even though it is placed in our head, the pituitary gland is not exactly a part of our nervous system, although it’s not exactly true that it isn’t. The pituitary gland communicates with other parts of the body through the hormones it produces and it oversees the healthy functioning of these parts of the body. These include the digestive tract, blood vessels and heart, muscle function and growth, genital function, thyroid, and adrenal function, even liver.
Indirectly, the function and hormone production of the pituitary gland eventually even affects our brain, either by the hormones that it produces on its own or by the hormones other glands produce by its order. For example, the adrenal gland can produce adrenaline which will make us feisty, or estrogen and testosterone which will either make us more interested in nail polishing or blade honing.
While it is in charge of healthy brain and body development, it is controlled by the brain itself, namely the hypothalamus, which produces chemical triggers that start or stop certain hormone production.
The Role of HGH
As you could imagine from this much, the pituitary gland produces human growth hormone. With HGH the body can do a lot because this stuff affects so many body processes.
For example, it is a vital part and triggers body growth. HGH is THE hormone that helps children grow into a size of an adult. Deficiencies in HGH can lead to slower and lesser growth, and the excess of this hormone can lead to gigantism in adulthood. The growth plan is dictated by several processes and in the vast majority of cases, these processes seal the growth somewhere in adulthood. So, there is no way to grow larger after these processes have ended.
In adulthood the production of HGH doesn’t stop, it just gets weaker little by little, until old age kicks in and it gets really low. In the meantime, HGH is in charge of various metabolic processes that maintain our body’s normal function.
One of these processes is the healthy development and maintenance of bone tissue. Through HGH the bones stay strong and sturdy. The same goes for our muscles. HGH is in charge of the creation of various proteins that also go into our muscles, so it’s in charge of maintaining and increasing the lean mass of our muscular system.
Okay, HGH is building, but it’s doing way more than that. It is involved in lipid metabolism as well, as it breaks down lipids so that the body can use energy from them, and then it’s involved in safely removing the side products from the bloodstream, along with triglycerides.
If you ever wondered why we need to take in our electrolytes regularly, you should know that we’d need to take much more if there wasn’t for HGH – this hormone regulates the retention of some of the most precious compounds within the body, like phosphate, sodium, etc. Without it, we’d need Gatorade much more often.
How pituitary gland doses HGH
The peculiar thing about HGH is that it is not constantly produced, but it’s rather produced in bursts. These bursts come several times during the day and it depends on the hypothalamus. The hypothalamus produces a hormone that triggers the pituitary gland to produce HGH in specific parts of the day (when sleeping for example).
Another way to trigger HGH production is during stress and physical strain. The body is then asked for better sugar metabolism and body rebuilding, so HGH is produced and released.
TB-500 is a synthetic peptide of the naturally occuring healing protein present in about all human and mammalian cells known as Thymosin Beta 4 (TB4). TB 500 is thought to have beneficial effects on wound healing, injury recovery, flexibility, and inflammation. Research indicated the effects of TB 500 are on blood cell and blood vessel development, cellular differentiation, and cell migration. The healing capability is due in large from the peptide’s regulation of actin, a cell building protein essential to healing and wound repair.
TB 500 is produced in the thymus gland and is found in high concentrations in wound fluids. Research demonstrates it has wound healing properties in addition to healing and repair of skin, cornea, and heart.
TB 500 is a naturally occurring peptide also found in high concentrations in blood platelets. TB-500 peptides for research are not growth factors; rather major actin regulating protein peptides. TB 500 plays an important role in protection, regeneration and remodeling of injured and/or damaged tissues. The gene that codes for Thymosin Beta-4 was noted in a study to be one of the first to be stimulated after an incident of injury.
Present in almost all human and animal cells, Thymosin Beta 4 is naturally occurring wound healing peptide. TB 500 , a synthetically made version of TB4 that facilitates comparable healing and recovery by helping building new blood vessels, muscle tissue fibers, blood cells, and facilitating cell migration. For a stressed and injured person, TB 500 can offer an extremely desirable wound healing effects.
No Horsing Around
TB-500 is a synthetic version of Thymosin Beta 4, a protein peptide that occurs naturally in the bodies of both animals and humans. Although TB-500 is available for research purposes, it is commonly used by many veterinarians who conduct clinical trials using TB-500 on horses. It is used to help promote healing from injury and reduce recovery time.
Dr. Allan Goldstein formulated thymosin alpha 1, in order to increase immune cell activity and subsequently thymosin bta 4 or TB-500, in order to accelerate healing and wound repair in animals, such as horses and ?
In racehorses TB 500 has shown significant reductions of inflammation and the inhibition or reduction of adhesions from injury.
The human use of thymosin began in 1974, with the first reported case being a young girl who was injected with thymosin due to a non functioning thymus gland. Since then, an increasing number of athletes and biohackers have been using thymosin all for the very same reasons of repair, reduction of inflammation and to speed up recovery.
Epitalon, also known as Epithalone or Epithalon, is a synthetic version of Epithalamin, a polypeptide naturally produced in the pineal gland.
The Epitalon peptide was discovered many years back by the Russian scientist Professor Vladimir Khavinson[i]. He carried out epitalon-related research for the following 35 years in both animal and human trials.
Primarily, the role of Epitalon is to increase natural production of telomerase. Telomerase is a natural enzyme that enables cells to reproduce telomeres – the protective parts of our DNA. In turn, this promotes the replication of DNA in order for the body to grow new cells and rejuvenate the old cells.
Younger people produce more telomerase than older people. In addition, they produce longer telomeres which leads to better cell health and replication.
As people age, telomerase production decreases and subsequently leads to cell replication decline. That’s where Epitalon comes in.
What Does Epitalon Do?
Epitalon definition: a mini protein that stimulates the production of telomerase.
How does Epitalon work? It works by regulating metabolism, heightening sensitivity of hypothalamus, stabilizing the function of the anterior pituitary and regulating melatonin levels in the body.
Epithalon peptide[ii] has a unique make-up of organisms determined by double-stranded DNA in the nucleus of the cells. At the tip of those DNA strands, you’ll find telomeres. They are responsible for preventing genetic information loss resulting from chromosome-shortening which happens with every cell separation.
Each time a cell separates, its replication is incomplete and consequently, telomeres get shorter. The more this happens, the more the telomeres shorten.
Numerous studies show that this shortening is linked to a slew of age-related diseases including cardiovascular disease and even early mortality in elderly people.
Known as the Epitalon fountain of youth due to its longevity effects, a high level of Epitalon results in overall wellness and wellbeing.
Effects of Epitalon
According to many studies[iii] conducted on both animals and humans, Epitalon is a substance biologically identical to the one produced by the human body. It can set the biological body clock of cells to zero in order for the cells to regain the reestablishment of optimal organ function and repair the body’s tissues.
Epitalon is a biopeptide created from four gero-protective amino acids (tetrapeptide: L-alanyl-l-glutamyl-l-asparagyl-glycine), which can be administered orally, intra-nasally, parenterally, sublingually, and also topically.
Russian researchers have discovered a lot about epithalon in recent years. For instance, they now know that it can reactivate telomerase production in cells. Furthermore, they know that it can also rejuvenate the whole body and promote health. They’ve even discovered that it can address the source of ageing.
Benefits of Epitalon Peptide
Scientific research proves that there are a number of Epitalon benefits. In short, these are the beneficial health effects of Epitalon peptide:
- Increases longevity and human lifespan
- Prevents age-related diseases such as dementia, heart disease, and cancer
- Promotes deeper sleep
- Improved skin health
- Strengthens muscle cells
- Speeds up healing
- Reduces lipid oxidation and reactive oxygen species
- Increases resistance to emotional stress
- Stabilizes melatonin levels in elderly people
Of course, robust research must be carried out on this protein in order to fully understand its full affects. However, from what scientists have uncovered about epithalon, it seems likely that it will soon be available for human use to treat and cure a number of health issues. Remarkably, scientists believe that Epitalon could soon be used as a treatment and a preventative medicine against cancer.
To further understand the health benefits of Epitalon peptide, we’re going to take a deeper look at its benefits and full scope of potential uses.
Epitalon Anti-Aging Effects
In 1992, Professor Vladimir Dilman and Dr. Ward Dean co-authored a paper entitled “The neuroendocrine theory of aging and degenerative disease,” which showed that biopeptide epitalon can increase the lifespan of rats by 25%.
These findings were then confirmed by various subsequent studies carried out by Professor Vladimir Khavinson, President of the St Petersburg Institute of Bio-regulation.
As discovered by these researchers, Epitalon increases lifespan thanks to its ability to connect several amino acids by peptide bonds. This can also stimulate brain activity and reduce tumor formations.
After 15 years of clinical observation, Khavinson’s research on elderly individuals showed that biopeptides significantly improved physiological function and decreased mortality by approximately 50%.
He also demonstrated that the epithalon biopeptide DNA interactions could control genetic functions and consequently successfully extend life expectancy.
Research shows that mice given Epitalon from the age of three months until their natural death increased their lifespan compared to mice given placebo. Epitalon treatment also lowered the frequency of chromosome abnormalities in the subjects’ bone marrow cells. Treatment with Epitalon also prevented leukaemia development in mice. Overall, the results of the study suggest that this peptide offers a powerful anti-aging effect and is safe for long-term use.
Numerous animal studies show that taking Epitalon results in the following effects:
- Regulated production of cortisol and melatonin in aging monkey, helping to stabilize the rhythm of cortisol secretion.
- Protected reproductive system and corrected impairment in the reproductive systems of rats.
- Preserved structure of the retina in retinitis pigmentosa.
- Inhibited proliferation of colon tumors in rats.
Epitalon Skin Effects
In addition to its anti-aging effects, Epitalon promotes better skin health.
Research by Dr Khavinson shows that epithalon can activate the cells[iv] responsible to repairing and maintaining the extracellular matrix that keeps skin healthy and youthful. The extracellular matrix is where collagen and elastin can be found – the two anti-aging powerhouses.
While there are a number of skin aging creams that claim to strengthen collagen in the skin, they do not penetrate the skin as deeply as Epitalon. Epithalon penetrates the cells themselves and promotes both growth and development of the fibroblasts that make proteins like collagen. In turn, this leads to optimum skin regeneration.
But it’s not just the vanity side of aging that epithalon peptide helps. It can also ward off disease, infection and damage. Aged skin is prone to tears and being brittle. Epitalon used on the skin can ward off those symptoms.
Epitalon for Retinitis Pigmentosa
Retinitis pigmentosa is a degenerative eye disease that leads to the degeneration of the rods in the retina. Rods are a type of receptor in the eye that convert light into chemical signals. In a clinic trial, research showed that Epitalon improved degenerative damage to the retina caused by the condition.
In studies on rats, Epitalon advances the function of retinal cells by preventing degeneration and preserving the rod structure.
As per a study on humans and rats, it proves that Epitalon is an effective treatment for retinitis pigmentosa. Still, further research is needed to confirm the findings.
Epitalon Sleep Effects
Epitalon can allegedly correct circadian rhythms. In case you are wondering, what are circadian rhythms, let us explain.
Essentially, circadian rhythms are mental, physical and behavioral changes that follow a daily cycle. Circadian rhythms respond mainly to light and darkness, which is why sleeping at night and being awake in the day is a good example of a light-related circadian rhythm. Nearly all living things have them – humans, animals, plants and even tiny microbes.
However, as humans age, those rhythms get disrupted and less prominent, due to decreased melatonin secretion.
In a small study on 14 elderly people[v], epitalon significantly improved melatonin production. It also altered its cycle to mimic those of young people.
Another study on aging monkeys also showed how Epitalon stimulated evening melatonin secretion and corrected the biological rhythm.
And because they determine our sleep patterns, it appears clear that Epitalon improves sleep dramatically in the process. Thus, Epitalon supplementation may improve the overall sleep quality and patterns of users.
Epitalon for Cancer
Epitalon research is still mainly in the animal stage and further human studies are required in order to better understand this peptide. However, research shows that Epitalon as a cancer treatment and for cancer prevention can be extremely effective. Of course, you should not attempt to replace conventional cancer therapies with this protein. Still, it is interesting to see how beneficial its effects are on a number of health conditions.
According to studies on rats, Epitalon peptide increases lymph flow and apoptosis while slowing down cancer growth.
In mice with mammary tumors, Epitalon reduced the number of mice with multiple tumors and reduced the maximum size of the tumors. Researchers also learned that peptide Epitalon decreased the expression of certain genes that can play a key role in the development of certain cancers such as breast cancer in both mice and humans.
Meanwhile, an additional study in mice found that Epitalon treatment reduced the number of mice with cancerous tumors. It also prevented cancer from moving to another location in the body — most interestingly, in all of the treated mice. As for the mice that did not receive the Epitalon administration, metastases were observed in 3 out of the 9.
How Is Epitalon Used?
Epitalon is typically administered via intravenous or intramuscular injection. It can also be administered transdermally.
While many results of Epitalon are promising and certainly show a lot of beneficial effects, the majority of research has been conducted in animals. In other words, Epitalon human research remains largely unresearched.
For this reason, Epitalon is not FDA approved. That doesn’t mean it is dangerous to use, but it does mean it hasn’t yet received the sufficient human research needed to approve it for human consumption.
Overall, Epitalon antiaging effects especially look interesting and indeed, promising. Clearly the studies show how effective Epitalon is for increasing lifespan and promoting youthfulness. It also appears to be a promising cancer prevention drug.
Side Effects of Epitalon
According to over 100 scientific studies on Epitalon, there were no adverse reactions to this peptide. Of course, as with all drugs, Epitalon side effects may occur in certain individuals, which is why you should proceed with caution. If adverse effects do occur, immediately stop using.
Currently not yet approved by the FDA, Epitalon should only be purchased and used by scientific professionals for research purposes only.
Fortunately, it is considered a safe drug with no dangerous side effects. Nevertheless, the research on Epitalon continues in order to ensure its full safety and scope of benefits.
Author info: The information provided in this article was taken from studies carried out by recognized researchers including Anisimov, Vladimir N., and Vladimir Kh. Khavinson, Frolov, D. S., D. A. Sibarov, and A. B. Vol’nova, Khavinson, V., Diomede, F., Mironova, E., Linkova, N., Trofimova, S., Trubiani, O., Sinjari, B., Chalisova, N. I., N. S., Zhekalov, A. O. Orlova, G. A. Ryzhak, Shatilo, and L. V. Magdich.
[i] Anisimov, Vladimir N., and Vladimir Kh. Khavinson. “Peptide Bioregulation of Aging: Results and Prospects.” Biogerontology 11, no. 2 (October 15, 2009): 139–149. doi:10.1007/s10522-009-9249-8.
[ii] Frolov, D. S., D. A. Sibarov, and A. B. Vol’nova. “Altered Spontaneous Electric Activity Detected in Rat Motor Neocortex after Intranasal Epitalon Infusions.” PsycEXTRA Dataset (2004). doi:10.1037/e516032012-081.
[iii] Khavinson, V., Diomede, F., Mironova, E., Linkova, N., Trofimova, S., Trubiani, O., … Sinjari, B. (2020). AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism. Molecules, 25(3), 609. doi:10.3390/molecules25030609
[iv] Chalisova, N. I., N. S. Linkova, A. N. Zhekalov, A. O. Orlova, G. A. Ryzhak, and V. Kh. Khavinson. “Short Peptides Stimulate Cell Regeneration in Skin During Aging.” Advances in Gerontology 5, no. 3 (July 2015): 176–179. doi:10.1134/s2079057015030054.
[v] Korkushko, O. V., V. Kh. Khavinson, V. B. Shatilo, and L. V. Magdich. “Effect of Peptide Preparation Epithalamin on Circadian Rhythm of Epiphyseal Melatonin-Producing Function in Elderly People.” Bulletin of Experimental Biology and Medicine 137, no. 4 (April 2004): 389–391. doi:10.1023/b:bebm.0000035139.31138.bf.Cite this article as: Research Peptides Scientists, “Epitalon (Epithalon) 10mg,” in ResearchPeptides.net, June 29, 2020, https://researchpeptides.net/product/peptides/epitalon-epithalon-10mg/.
Epitalon Research Peptides Scientists
- Dmitry A.Sibarov Ph.D.Epitalon (Epithalone or Epithalon)Biologist working in the area of neuroscience in I.M.Sechenov Institute of Physiology and BiochemistryD. A. Sibarov has a Ph.D. from the St.Petersburg State University. Dmitry A.Sibarov Ph.D. currently works at the Biotechnologies Inc. company, Russia and has 2 years experience in researching Neuron Activity at the Pavlov Institute of Physiology. One of their notable works include “Effects of intranasal administration of epitalon on neuron activity in the rat neocortex”. Published online Nov 2007. doi:https://doi.org/10.1007/s11055-007-0095-3 [PubMed]
Website | Researchgate | Scholar Google
- Vladimir Khavinson Ph.D.EpitalonVladimir Khavinson is a Professor, Treasurer of the European region of the International Association of Gerontology and Geriatrics; Main gerontologist of the Health Committee of the Government of Saint Petersburg, Russia; Director of the Saint Petersburg Institute of Bioregulation and Gerontology; Vice-president of Gerontological Society of the Russian Academy of Sciences; Head of the Chair of Gerontology and Geriatrics of the North-Western State Medical University, St-Petersburg; Colonel of medical service (USSR, Russia), retired.Vladmir Khavison has a Doctor of Medicine from the Voyenno-Meditsinskaya Akademiya Imeni S. M. Kirova. Vladimir Khavinson Ph.D. currently works at the St. Petersburg Institute of Bioregulation and Gerontology and has 4 years experience in researching Gene Expression and Protein Synthesis at the St. Petersburg Institute of Bioregulation and Gerontology. One of their notable works include “AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism”. Published online 30 Jan 2020. doi:https://doi.org/10.3390/molecules25030609 [PubMed]
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Peptide research is proving that short chain amino acids like CJC-1295 combined with Ipamorelin are about to become the most effective anti-aging and weigh-loss treatments in the history of mankind.
These two peptides have already proven to be game changers for inflammatory conditions, energy deficiencies, mood disorders, and sleep issues. But, now research scientists and cutting edge medical doctors feel their anti-aging and weight loss benefits are so incredibly effective that they will soon become the #1 go-to weight loss and anti-aging treatments in the 2nd half of the 21st century.
Sometime before midnight as well as the early morning Growth hormone is released into the bloodstream from the anterior pituitary gland.
Our body’s natural growth hormone levels peak when we are about 20 years old and slowly decrease but stays close to to that level until around 30 years old at which time the HGH level begins to decrease at a rate of about 15% a year.
As the body ages, both men and women tend to gain weight, lose energy, and decrease muscle mass. This is due to our natural growth hormone levels that have decreased year over year as we age.
How long does it take for CJC-1295 / Ipamorelin to work?
Research shows CJC-1295/ Ipamorelin short term (3-6 months) has proven to have fat loss benefits and provide overall improvements in body composition. CJC-1295/Ipamorelin increases fat metabolism, so when aging and low HGH levels are present and this starts to become a factor in a person’s ability to lose weight, these peptides can create a more efficient and sometimes faster process of loosing adipose tissue.
Thymosin is a hormone secreted from the thymus. Its primary function is to stimulate the production of T cells, which are an important part of the immune system. Thymosin also assists in the development of B cells to plasma cells to produce antibodies. The predominant form of thymosin, thymosin beta 4, is an actin, a cell building protein. One of the main mechanisms of action of Thymosin Beta-4 is its regulation of Actin. This cell-building protein is an essential component of cell structure and movement which leads to its role in tissue repair. Tβ 4 has been found to play an important role in protection, regeneration, and remodeling of injured or damaged tissues. After an injury, Tβ 4 is released by platelets and numerous other types of cells to protect the most damaged cells and tissues and to reduce inflammation and microbial growth.
Benefits of Thymosin beta 4:
- Calms muscle spasms
- Enhances muscle tone
- Increased exchange of substances between cells
- Encourages tissue repair
- Stretches connective tissue
- Helps maintain flexibility
- Reduced inflammation of tissue in joints
- Encourages the growth of new blood cells in tissue
- Increased endurance and strength
- Prevents the formation of adhesions and fibrous bands in muscles, tendons, and ligaments
Recent studies have revealed that the first gene to be upregulated after an injury is a Tβ4 gene. As the body begins the recovery process, Tβ4 aids in the creation of new vessels in the injured area, which carry blood, nutrients, and reparative substances to the site. Tβ4 also has anti-inflammatory properties and works to decrease the amount of inflammatory substances, called cytokines. Inflammation plays a large role in many of the symptoms associated with a number of other conditions (i.e., Lyme disease, CFS, FM, autoimmune diseases, infections, etc.), making the potential impact of Tβ4 quite extensive.
The discovery of the role of Tβ4 in the process of immune regulation has lead to its use as a valuable therapeutic agent. Tβ4 has been used in the treatment of HIV, AIDS, Influenza, colds, and various infections. It has been utilized in the management of various inflammatory conditions, as well as part of treatment following a heart attack due to its cardio and neuroprotective effects.
Tβ4 is very well tolerated and has not been found to cause any significant side effects. It can be taken on its own or in conjunction with an existing therapy, making it a versatile and valuable peptide.
Epitalon is derived from Epithalamin (Epithalamine), a naturally occurring polypeptide in the body, which is produced in pineal gland. A very valuable and unique main property of Epitalon is its ability to increase telomerase activity in somatic cells. This helps cells reproduce telomeres, which are the essential “protective parts” of our DNA, which eventually results in a slowdown in the aging process.
In addition, scientific studies have also shown other great possible benefits of Epitalon as prevention of cancer and age-related diseases, restoration and normalization of melatonin levels, promotion of deeper sleep and strong anti-oxidant properties. Epitalon is patented by its discoverer Professor Khavinson and was approved for general use in Russia in 1990 and has since been used in gerontology. Many scientific studies and clinical trials of Epitalon have been conducted in both animals and humans, and no adverse side effects have ever been reported to date.
MECHANISM OF ACTION OF EPITALON
Telomerase activator peptide Epitalon directly stimulates cells in the body to produce a telomerase enzyme, that renew and extends telomeres at the ends of chromosomes. This ultimately leads to a slowing of the aging of cell populations, and the aging of cell populations correlate with the overall physical aging of an organism. Clinical studies conducted with Epitalon have shown that administration of Epitalon to mammals has not only reversed the symptoms of aging but also reversed many age-related diseases. Epitalon has also been shown to help restore and normalize melatonin production by the pineal gland, as well as restoring the normal circadian rhythm of cortisol production, both of which result in better sleep at night.
DNA & CHROMOSOMES
DNA (Deoxyribonucleic acid) is a molecule composed of 2 polynucleotide chains that coil around each other to form a double helix carrying genetic instructions for the development, functioning, growth and reproduction of all known organisms and many viruses. DNA and RNA (Ribonucleic acid) are nucleic acids. Alongside proteins, lipids and complex carbohydrates (polysaccharides), nucleic acids are one of the four major types of macromolecules that are essential for all known forms of life.
Chromosome is a DNA molecule with part or all of the genetic material (genome) of an organism: Within eukaryotic cells (animals, plants, fungi and protists), DNA is organized into long structures called chromosomes. Before typical cell division, these chromosomes are duplicated in the process of DNA replication, providing a complete set of chromosomes for each daughter cell. Eukaryotic organisms store most of their DNA inside the cell nucleus as nuclear DNA, and some in the mitochondria as mitochondrial DNA or in chloroplasts as chloroplast DNA.
Telomere is important region of repetitive nucleotide sequences at each end of a chromosome, which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes. However, as a result of each cell division, the ends of the telomeres are shortened: During chromosome replication, the enzymes that duplicate DNA cannot continue their duplication all the way to the end of a chromosome, so in each duplication the end of the chromosome is shortened (this is because the synthesis of Okazaki fragments requires RNA primers attaching ahead on the lagging strand). This means, each cell division (each time a cell undergoes mitosis), the telomeres on the ends of each chromosome again shorten. After many divisions, the telomeres reach a critical length, resulting in the cell eventually losing its ability to divide further to replace worn, damaged or diseased cells. Further cell division becomes impossible and the cell becomes senescent. At this point, the cell reached its so-called Hayflick limit.
THE HAYFLICK LIMIT
The Hayflick limit, or Hayflick phenomenon, is the number of times a normal human cell population will divide before cell division stops. The concept of the Hayflick limit was advanced by American anatomist Leonard Hayflick in 1961, at the Wistar Institute in Philadelphia, Pennsylvania, United States. Hayflick demonstrated that a normal human fetal cell population will divide between 40 and 70 times in cell culture before entering a senescence phase. The aging of cell populations appears to correlate with the overall physical aging of an organism.
Hayflick was also the first to report that only cancer cells are immortal. Cellular senescence does not occur in most cancer cells due to expression of an enzyme telomerase, when telomerase extends telomeres / preventing the telomeres of cancer cells from shortening and by this way giving them infinite replicative potential. One of the proposed treatment for cancer is the usage of telomerase inhibitors in the cancer cells, that would prevent the restoration of their telomeres, and allows the cancer cells to die like other body cells.
Telomerase is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3′ end of telomeres. It is a reverse transcriptase enzyme that carries its own RNA molecule (e.g., with the sequence 3′-CCCAAUCCC-5′ in Trypanosoma brucei) which is used as a template when it elongates telomeres. Telomerase is active in gametes and most cancer cells, but is normally absent from, or at very low levels in, most somatic cells.
Telomerase restores short bits of DNA known as telomeres, which are otherwise shortened when a cell divides via mitosis. In normal circumstances, where telomerase is absent, if a cell divides recursively, at some point the progeny reach their Hayflick limit, which is believed to be between 40–70 cell divisions. At the limit the cells become senescent and cell division stops.
But Telomerase allows each offspring to replace the lost bit of DNA, allowing the cell line to divide without ever reaching the limit – allowing senescent cells that would otherwise become postmitotic and undergo apoptosis to exceed the Hayflick limit and become potentially immortal, as is often the case with cancerous cells.
Embryonic stem cells express telomerase, which allows them to divide repeatedly and form the individual. In adults, telomerase is highly expressed only in cells that need to divide regularly, especially in male sperm cells but also in epidermal cells, in activated T cell and B cell lymphocytes, as well as in certain adult stem cells, but in the great majority of cases somatic cells do not express telomerase.
The pineal gland is a small endocrine gland in the brain of most vertebrates. It is located in the epithalamus, near the center of the brain, between the two hemispheres, tucked in a groove where the two halves of the thalamus join. The pineal gland is one of the neuroendocrine secretory circumventricular organs in which there does not exist the blood–brain barrier at the capillary level.
The primary function of the pineal gland is to produce Melatonin, that has various functions in the central nervous system, the most important of which is to help modulate sleep patterns. The pineal gland also produces polypeptide Epithalamin, that stimulates cells in the body to produce a telomerase enzyme, that extends telomeres at the ends of chromosomes in their DNA. This ultimately leads to a slowing of the aging of cell populations.
Epitalon was discovered and developed by the Russian scientist and gerontologist Professor, Doctor of Medical sciences Vladimir Khavinson of St. Petersburg Institute of Bioregulation and Gerontology, whose research is focused on the development of peptide preparations used to restore function in various organs in order to prevent and reverse the aging process. Epitalon was identified as active component of a bovine pineal gland extract (known as Epithalamin).
Low-molecular peptides isolated from pineal gland and Epithalamin of animals were studied in different biologic models. Most all performed scientific studies and clinical trials of Epitalon and Epithalamin have been conducted just by already mentioned St. Petersburg Institute of Bioregulation and Gerontology in Russia, primarily overseen by Professor Vladimir Khavinson, who has been involved in this research already for over 35 years, and has merit not only in the discovery of epitalon, but also in its highly advanced scientific and clinical review. Throughout this time, Epitalon has been extensively investigated in animal and human clinical trials and today is one of the best scientifically investigated peptides.
SCIENTIFIC STUDIES, CLINICAL TRIALS AND EPITALON RESULTS
Scientific studies in animals:
An in vivo study in aging mice found that epitalon treatment significantly reduced the incidence of chromosomal aberrations, both for wild-type mice and for mice characterized by an accelerated aging phenotype, which is consistent with increases in telomere length.
Another study in aging rats found that epitalon increased the activities of the antioxidant enzymes superoxide dismutase, glutathione peroxidase, and glutathione-S-transferase. In male rats, epithalamin increased total antioxidant capacity by 36% and superoxide dismutase (SOD, a powerful endogenous antioxidant) by 19%. Oxidative stress, which occurs when the body has a deficit in antioxidants to counteract the effects of free radicals (damaging molecules that are missing electrons), plays a causative role in many diseases, including heart disease, cancer, diabetes, and even neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases. One of the most potent endogenous antioxidants produced by the body is Melatonin. Epitalon’s antioxidant effects are thought to be in part due to its ability to stimulate Melatonin production as well as mechanisms other than through the action of Melatonin.
Epitalon reduced the number of spontaneous tumors and the number of metastases in mice that did develop spontaneous tumors in an experiment on one-year-old female C3H/He mice, and is speculated to have oncostatic and anti-metastatic properties.
In a study of chickens subjected to neonatal hypophysectomy and subsequent maturation, epitalon promoted the recovery of the morphological structures of the thymus, as well as the structure and function of the thyroid gland. Epitalon appears to increase the proliferation of lymphocytes in the thymus, putatively increasing production of interferon gamma by T-cells. Another study in aging rats demonstrated extension of life span for rats subjected to constant illumination or to a natural light regimen typical of northern regions.
Scientific studies in humans:
In human clinical studies, epitalon and epithalamin both significantly increased telomere lengths in the blood cells of patients of ages 60-65 and 75-80, and their efficacy was comparable to one another.
Epitalon and epithalamin appear to restore melatonin secretion by the pineal gland in both aged monkeys and humans.
A human clinical trial conducted on a sample of retinitis pigmentosa patients found that epitalon produced a positive clinical effect in 90% of cases in the treated group.
In another human clinical trial conducted on a sample of pulmonary tuberculosis patients, epitalon did not appear to correct pre-existing structural aberrations of chromosomes associated with telomere degradation, but did appear to exert a protective effect against the future development of additional chromosomal aberrations.
A human prospective cohort study conducted on a sample of 266 people over age 60 demonstrated that treatment with epithalamin, the pineal gland extract upon which epitalon is based, produced a 1.6–1.8-fold reduction in mortality during the following 6 years, a 2.5-fold reduction in mortality when combined with thymulin, and a 4.1-fold reduction in mortality when combined with thymulin and administered annually instead of only once at study onset.
Another prospective cohort study on a sample of 79 coronary patients spanning in excess of 12 years found improved metrics of physical endurance, circadian rhythm, and carbohydrate and lipid metabolism in the treated group relative to the control group following 3 years of biannual epithalamin treatments, as well as a 50% lower rate of cardiovascular mortality, a 50% lower rate of cardiovascular failure and serious respiratory disease, and a 28% lower rate of overall mortality.
Elongation of telomeres by epitalon was sufficient to surpass the Hayflick limit in a cell culture of human fetal fibroblast cells, extending their proliferative potential from termination at the 34th passage in the control cell population to beyond the 44th passage in the treated cell population, while increasing the lengths of their telomeres to levels comparable to those of cells in the original culture.
Epitalon induces decondensation of heterochromatin near the centromeres in cultured lymphocytes originating from samples taken from humans of ages 76 to 80 years.
Epitalon appears to inhibit the synthesis of the MMP9 protein in vitro in aging skin fibroblasts.
SCIENTIFICALLY INVESTIGATED POSSIBLE BENEFITS OF EPITALON
Slows the aging of cell populations by stimulating the renew and elongation of telomeres at the ends of chromosomes in DNA
Slowing of aging / anti-aging effect, rejuvenation
Prevention of cancer and age-related diseases
Restores and normalizes Melatonin production by the Pineal gland
Strong anti-oxidant properties, protects against oxidative stress, act against the effects of free radicals
Increases the activities of the antioxidant enzymes superoxide dismutase, glutathione peroxidase, and glutathione-S-transferase
Reduces lipid oxidation and ROS (reactive oxygen species) together with normalization of T cell function (increases interferon gamma production by T cells)
Better, deeper sleep and its quality
Improves metrics of physical endurance, circadian rhythm, and carbohydrate and lipid metabolism
Healthier skin, inhibits the synthesis of the MMP9 protein in vitro in aging skin fibroblasts
Positive clinical effect in Retinitis pigmentosa disease
EPITALON POSSIBLE SIDE-EFFECTS
Performed scientific studies and clinical trials to date have not shown any significant side, undesirable or toxic effects when investigating the Epitalon peptide.
What is Epitalon used for?
Epitalon is used for increase the natural production of telomerase, a natural enzyme that helps cells reproduce telomeres, which are the protective parts of our DNA. This ultimately leads to a slowing of the aging of cell populations, and the aging of cell populations correlate with the overall physical aging of an organism. However, epitalone can also be used to restore and normalize melatonin levels or to protect against cell oxidative stress.
Can Epitalon slow down aging?
Scientific research and performed clinical trials have demonstrated Epitalon slows the aging and has strong anti-aging properties.
Can Epitalon prevent cancer?
Yes, Epitalon has the ability to prevent cancer.
Can Epitalon improve sleep?
Yes, Epitalon supports and normalize production of Melatonin, which leads to a better and deeper sleep.
How do you administer Epitalon?
Epitalon is usually administered by intravenous, intramuscular or transdermal / subcutaneous (under the skin, through the skin) injection. Oral administration is not effective because the peptides are broken down / cleaved in the gastrointestinal tract. This means: They cannot pass through the gastrointestinal tract in functional and intact state, up to the bloodstream to exert their effects.
Where can I buy Epitalon?
We offer Epitalon of the highest purity for bargain price.
Does Epitalon have side effects?
Clinical trials to date have not shown any significant side, undesirable or toxic effects when Epitalon was used.
In the scientific studies and clinical trials performed, the optimal dose of Epitalon is often reported as 5 – 10 mg daily, over a period of 10-20 days. The frequency of administration is one injection per day at lower doses and two injections per day at higher doses, which may be divided between morning and evening. Each course of use should be followed by a pause of 4-6 months before the course is repeated
What Is Epitalon?
Epitalon is a synthetic peptide made of four amino acids (alanine, glutamic acid, aspartic acid, and glycine), that is based on a natural peptide called epithalamin extracted from the pineal gland. It was synthesized by Vladimir Khavinson, a Russian professor and gerontologist, whose research focused on the development of peptide preparations used to restore function in various organs in order to prevent and reverse the aging process. He is currently the Director of the Saint Petersburg Institute of Bioregulation and Gerontology
Khavinson first extracted Epithalamin from the pineal gland of calves. However, due to the inherent limitations in production, he formulated a synthetic version of the peptide called Epitalon.
How Is Epitalon Used?
Epitalon is usually administered via intravenous or intramuscular injection or transdermally (through the skin), as peptides are broken down in the digestive tract and therefore unable to enter the bloodstream, where they can exert their effects, intact.
Although some results are promising, most of the research has been conducted in animals and cells, meaning that both the potential health benefits and safety profile of Epitalon remain largely unresearched. Never take Epitalon without consulting your doctor or use it as a replacement for approved medical therapies.
What the Research Shows for Epitalon
1) Retinitis Pigmentosa
Retinitis pigmentosa is a genetic, degenerative eye disease that results in the degeneration of the rods in the retina. Rods are one of two types of receptors in the eye (the other one being cones) that convert light into chemical signals that can be processed by the brain.In a clinical trial, Epitalon improved degenerative damage to the retina caused by this condition in 90% of the patients . In rats, Epitalon improves the function of retinal cells by preserving their structure and preventing degeneration .
A single study using humans and rats cannot be considered sufficient evidence to support this potential use of Epitalon. Further clinical research is needed to confirm these preliminary findings.
2) Correcting Circadian Rhythms
As we age, our circadian rhythms become disrupted and less pronounced, coinciding with decreased melatonin secretion and altered sleep cycles .
In a small trial on 14 elderly people, epithalamin improved melatonin production and altered its cycle and peak concentrations to resemble those of young people .
In aging monkeys, Epitalon stimulated evening melatonin secretion and reestablished the circadian rhythm, which is associated with cortisol release .
Again, only a small clinical trial and an animal study have tested this potential health benefit. Larger, more robust clinical trials are required.
Animal and Cell Research (Lack of Evidence):
No clinical evidence supports the use of Epitalon for any of the conditions listed in this section. Below is a summary of the existing animal and cell-based research, which should guide further investigational efforts. However, the studies listed should not be interpreted as supportive of any health benefit.
3) Increasing Lifespan
When the peptide was administered to fruit flies during the larval stage, it increased the average lifespan by 11-16 percent .
In a study on rats exposed to equal amounts of light and darkness, varying amounts of light and darkness, or permanent light illumination, Epitalon increased maximal lifespan in all three groups by 68 days, 95 days, and 24 days, respectively, in comparison to controls.
In mice with high blood pressure, injections of Epitalon did not affect the average lifespan of the mice but did increase the maximal lifespan by 12.3% .
Cell-based studies found that Epitalon increases telomerase activity. This enzyme adds more nucleotides to the protective sequences at the end of chromosomes (telomeres), thus allowing cells to divide and grow longer .
4) Increasing Enzyme Activity
A decrease in pancreatic enzymes has been shown to occur in elderly individuals . In both young and old rats, Epitalon increased the activity of enzymes that digest protein and sugar, with the effect being more pronounced in the older rats . Another study found that the peptide increased enzyme activity in the small intestine of aged rats .
Below, we will discuss some preliminary research on the anticancer activity of Epitalon. It’s still in the animal stage and further clinical studies have yet to determine if this peptide is useful in cancer therapies. Do not under any circumstances attempt to replace conventional cancer therapies with Epitalon.
When Epitalon was given to rats with colon cancer, the peptide increased lymph flow (containing white blood cells) and apoptosis (programmed cell death), while it slowed cancer growth .
In mice with mammary tumors, Epitalon significantly decreased the number of mice with multiple tumors and decreased the maximum size of tumors in comparison to control mice . The researchers also found that the peptide reduced the expression of certain genes that, when over-activated, play a key role in the development of breast cancer in both mice and humans.
Another study in mice found that treatment with Epitalon reduced the number of mice with malignant tumors (cancerous tumors) and prevented cancer from metastasizing (moving to another location in the body) in all of the treated mice. In contrast, metastases were observed in 3 out of the 9 mice that did not receive treatment with Epitalon .
Oxidative stress, which occurs when the body has a deficit in antioxidants to counteract the effects of free radicals (damaging molecules that are missing electrons), plays a causative role in many diseases, including heart disease, cancer, diabetes, and even neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases .
One of the most potent antioxidants produced by the human body (endogenous antioxidants) is melatonin .
Epitalon’s antioxidant effects are thought to be in part due to its ability to stimulate melatonin production as well as mechanisms other than through the action of melatonin .
In male rats, epithalamin increased total antioxidant capacity by 36% and superoxide dismutase (SOD, a powerful endogenous antioxidant) by 19% .
When epithalamin was incubated with blood taken from breast cancer patients, they showed increased activity of antioxidant enzymes and levels of antioxidative vitamins .
While some preclinical studies on Epitalon look promising, there is still a lot of research that needs to be conducted in healthy and diseased individuals. Epitalon has not been approved by the FDA but is available in supplements Talk to your doctor before taking Epitalon or any other supplements, especially if they have been insufficiently researched.
About the Author:
Dr. Puya Yazdi is a physician-scientist with 14+ years of experience in clinical medicine, life sciences, biotechnology, and nutraceuticals.
As a physician-scientist with expertise in genomics, biotechnology, and nutraceuticals, he has made it his mission to bring precision medicine to the bedside and help transform healthcare in the 21st century.He received his undergraduate education at the University of California at Irvine, a Medical Doctorate from the University of Southern California, and was a Resident Physician at Stanford University. He then proceeded to serve as a Clinical Fellow of The California Institute of Regenerative Medicine at The University of California at Irvine, where he conducted research of stem cells, epigenetics, and genomics. He was also a Medical Director for Cyvex Nutrition before serving as president of Systomic Health, a biotechnology consulting agency, where he served as an expert on genomics and other high-throughput technologies. His previous clients include Allergan, Caladrius Biosciences, and Omega Protein. He has a history of peer-reviewed publications, intellectual property discoveries (patents, etc.), clinical trial design, and a thorough knowledge of the regulatory landscape in biotechnology.He is leading our entire scientific and medical team in order to ensure accuracy and scientific validity of our content and products.
Composed of 4 amino acid chains Epitalon is a synthetic derivative of epithalamin and a potential modulator of telomerase, the enzyme that maintains and protects the telomere caps at the ends of chromosomes (strands of DNA). Research suggests that epithalon induces telomere elongation and may fight off the effects of aging as a result.
The Epitalon peptide has proven to not only produce a relatively large amount of new telomerase, they produce longer telomeres strands which are in the better cell health and replicate faster.
Introducing the Epitalon peptide into the body appears to stop the degeneration of the telomeres, which naturally happens and is one of the main reasons humans age and their health declines.
In the next article we will be investigating how Epitalon and another peptide play out a symbiotic role in regulating metabolism, increasing the sensitivity of hypothalamus to its natural hormonal levels, normalizing the function of the anterior pituitary and regulating the levels of gonadotropins and melatonin in the body.
Please direct your questions to the comments section or on my facebook messenger. Blessings, Bobby
- 4 cups young baby coconut meat – You can buy young baby coconuts at most Asian markets. These are sometimes called Thai Coconuts
- 1 1/2 cups of the baby coconut water – You can enjoy drinking the remaining coconut water leftover from opening your coconuts
- 1/4 cup of rejuvelac – If you do not have rejuvelac break open 2-3 pro-biotic capsules and use them in-place of the rejuvelac
- Put all your ingredients in to your blender and blend till smooth, usually about 1 minute at high speed.
- Pour in to a bowl and place in your dehydrator. Set you temp to 105 degrees and set your time for 4 hours, or until the mixture has the fluffy texture of homemade yogurt. You can alway set the mixture outside if its warm or in the oven at 200 degrees with the door cracked.
Refrigerate for 2 hours, then enjoy alone or with your favorite fruit or berries. Blending in your fruit or berries creates amazing fruit smoothies. I promise, once you make your own vegan coconut yogurt you will not go back to dairy based yogurts.
Coconut Yogurt Benefits
- Fermented live cultures
- Aids digestive health.
- Protects from infections
- May reduce the risk for colon cancer
- Lowers serum cholesterol
- Good source of minerals, vitamins, dietary fiber
- Enhances the immune system providing up regulated protection from certain viruses and bacteria.
If you would like more information on probiotic foods, email me and I will send you more information.
Happy 4th of July. Sending Love and Blessings,
“Until man duplicates a blade of grass, nature can laugh at his so-called scientific knowledge.” Thomas A. Edison
Wheatgrass consumption for medicinal purposes has been in use for more than 5000 thousand years. The ancient Egyptian and Mesopotamian civilizations, designated wheatgrass as a sacred plant that was used in more thant 100 healting modalites. The Egyptians considered it the elixor of life and the Chinese used it for blood detoxification.
A shot of wheatgrass is 70% chlorophyll, 12% water, 12% protein, 2.2crude fiber, 2% fat, 1.8% minerals. Organically grown wheatgrass contains 92 of the 102 known minerals. Wheatgrass also contains 13 essential vitamins and minerals, and 20 plus amino acids are found in wheatgrass.
Dr. Ann Wigmore taught, when we drink wheatgrass juice, regularly we feel a positive difference in strength, endurance, health, and spirituality, and experience a sense of well-being.
The enzymes, amino acids, and chlorophyll in wheatgrass juice contain antibacterial compounds that are especially good at destroying anaerobic bacteria that thrive in oxygen-poor blood and tissue.
Science has proven that chlorophyll arrests growth and development of unfriendly bacteria. Because wheatgrass is 70% Chlorophyll, it makes short work of bacteria and can be used inside and outside the body as a healer.
Dr. Birscher, a research scientist, called the chlorophyll in wheatgrass “concentrated sun power.” He said, “Chlorophyll increases the function of the heart, affects the vascular system, the intestines, the uterus, and the lungs.”
Today, we know Wheatgrass is one of the most potent sources of living chlorophyll available. Wheatgrass juice is great for blood disorders of all kinds, including anemia. A recent study in The Journal of Alternative and Complementary Medicine found that supplementing with the natural antioxidants found in wheatgrass “holds great promise in overcoming the ill effects of oxygen toxicity,.”
Some Very Beneficial Wheatgrass Juice Benefits.
- Wheatgrass Juice reduces high blood pressure and enhances the capillaries.
- Wheatgrass juice can be taken by a human or animal orally, vaginally, as a poultice and as a colon implant. Wheatgrass implants (enemas) are great for healing and detoxifying the colon walls. The implants also heal and cleanse the internal organs.
- How to do wheatgrass implants – After doing a pure water enema, wait 10 minutes and then implant 3-6 ounces of wheatgrass juice. Retain it for 20 minutes.
- Enema’s containing wheatgrass has proven to eliminate constipation ans purify the blood.
- The chlorophyll in wheatgrass goes into the bloodstream, fills the tissues, extricates dying and diseased cell, making room for new healthy live cells, rejuvenating tissues, thus slowing the aging process.
- The liquid chlorophyll in wheatgrass washes unwanted drug deposits from the body.
- Wheatgrass combined with a raw living foods diet cures acne in days and removes scars after it has been ingested for six to eight months.
- Wheatgrass juice acts as a detergent in the body and is used as a body deodorant.
- A small amount of wheatgrass in the human diet helps prevents tooth decay.
- Toxins in and on the body are more easily neutralized by the chlorophyll in wheatgrass.
- The chlorophyll in the wheatgrass helps purify the liver.
- Diabetics benefit from the chlorophyll in the wheatgrass as it balances blood sugar.
- It is easily absorbed and carries high levels of oxygen and light energy to the body. Being loaded with chlorophyll and chlorophyll being the first product of light, therefore means wheatgrass contains massive amounts of light energy.
- Chlorophyll is the lifeblood of wheatgrass and is quickly assimilated into our bodies and is just one molecule different in structure than our own blood.
- Being loaded with oxygen wheatgrass helps us to think clearer as it feeds our brain, tissues, and organs with optimal levels of chlorophyll based oxygenated nutrients.
- The amino acids in wheatgrass are absorbed directly into the blood and act to neutralize toxic substances like cadmium, nicotine, strontium, mercury and polyvinyl chloride (a type of plastic) by changing them into insoluble salts that the body can eliminate quickly,rejuvenating the tissues, thus slowing the aging process.
- Wheatgrass also rebuilds the bloodstream. Studies of various animals have shown the chlorophyll in wheatgrass raises the red blood cell count. The red cell count was returned to normal within 4 to 5 days of the administration of chlorophyll, even in those animals which were known to be extremely anemic or low in red cell count.
- Just soaking in a bathtub of wheatgrass bath for a ½ hour for each day for 5 days will raise the red blood cell count.
- Dr. Ann Wigmore proved that wheatgrass takes only minutes to ge digested and therefore uses up very little of the body’s energy.
- Wheatgrass is also a powerful heavy metal detoxifier and studies have shown to remove heavy metals from the body. Wheatgrass also has a positive effect on sterility and can restore fertility. (The high magnesium content in chlorophyll builds enzymes that restore the sex hormones.)
- Wheatgrass juice held in the mouth for 5 minutes will help eliminate toothaches. It pulls poisons from the gums
- Do what Dr. Ann Wigmore did and drink Wheatgrass Juice to keep your hair from graying.
- Toxic side effects – Wheatgrass has no known toxic side effects and is a powerful full body detoxifier.
- In the American Journal of Surgery (1940), Benjamin Gruskin, M.D. recommends chlorophyll for its antiseptic benefits.
- Clears up foul smelling odors.
- Neutralizes Strep infections.
- Heals wounds.
- Hastens skin grafting.
- Cures chronic sinusitis.
- Overcomes chronic inner-ear inflammation and infection.
- Reduces varicose veins.
- Heals leg ulcers.
- Eliminates impetigo and other scabby eruptions.
- Heals hemorrhoids and rectal sores.
- Treats inflammation of the uterine cervix.
- Gets rid of parasitic vaginal infections.
- Reduces typhoid fever symptoms.
- Cures advanced pyorrhea in many cases.
- Dissolves the scars that are formed in the lungs from breathing acid gasses.
- The effect of carbon monoxide is minimized since chlorophyll increases hemoglobin production.
- Gargle Wheatgrass Juice for a sore throat.
- Cut out spending money on costly probiotics as wheatgrass juice is high in live enzymes.
- As a poultice, wheatgrass fiber can provide amazing results on ulcerated skin, boils, acne, and infections.
- Gum disease of the mouth is helped by rinsing and applying a wheatgrass poultice. Use the fiber(pulp) leftover from juicing to make a poultice.
- B17 in wheatgrass has been shown to have positive effects on the immune system.
- Help rebuild and balance the immune system , enabling the body to strengthen itself so it can eliminate cancer cells.
- Wheatgrass may be an anti-cancer super food, precisely due to selenium and laetrile which are anti-cancer compounds found in wheatgrass.
- Cancer cells like acidic atmosphere and wheatgrass help alkalize the body.
- With wheatgrass, the body becomes a more difficult place for cancer cells to continue thriving.
- Accompanied Dr. Ann Wigmore’s, spirit we continue showing people how to take charge of their lives, drink wheatgrass, and recover from chronic and life-threatening health disorders in 2021.
Wishing everyone a wonderful 4th of July holiday here in the USA and to our friends around the world may you be blessed in everything you do.
Blessings to all. Bobby
With all the recent questions about peptides, I felt that I should clarify that peptides are simply a sequence of amino acids. In the 21st century we will continue to see further breakthroughs in way we will use peptides to optimize our health and healing and lifestyles.
I am particularly excited about BPC-157 and its wide array of health benefits, as it’s not simply a vascular endothelial growth factor analog it is often misrepresented as; Rather than acting like a regular VEGF it will promote the complex physiological processes that occur during wound healing and tissue regeneration and repair – both inside and outside of the gastrointestinal tract. BPC-157 is proving to be a fascinating medical breakthrough for anyone who is interested in optimizing fat loss, strengthening, repairing and rebuilding muscle tissue, slowing the aging process, balancing and strengthening their immune system, healing stomach and intestinal issues, strengthening the heart muscle and insuring brain plasticity and ensuring neuroprotective health.
BPC-157 may promote the regeneration of the cells of the intestinal wall (intestinal health | Sikiric 2018)
BPC-157 may promote and accelerate muscle, tendon and bone healing (sports and other tissue and bone injuries | Brcic 2009, Krivic 2008, Sebecic 1999)
BPC-157 aids in the repair and replacement of atherosclerotic endothelial cells (cardiovascular health | Sikiric 2018)
BPC-157 promotes, optimizes and accelerates wound healing (skin health and organ damage | Huang 2015; Stupnisek 2015)
BPC-157 prevents and reverses lesions of the intestinal tract, liver, and even brain as they can occur in response to the (ab-)use of certain pain medications (general organ health | Drmic 2018) and the cardiovascular side effects of anti-psychotics (heart health | Strinic 2017)
BPC-157 heals (stress-induced) ulcers and fistulas as they are increasingly common due to our stressful (this refers to “stress” as general oxidative stress) lifestyles (GI health and beyond | Szabo 2017; Grgic 2016)
BPC-157 serves as a remedy for a plethora of central nervous system disorders that originate in the gut by (a) the local repair of the intestinal lining and (b) direct neuroprotective effects in the brain (brain & CNS health | Sikiric 2016)
BPC-157 can be paired with other peptides and compounds for maximum results:
- Thymosin Alpha-1 and Thymosin Beta-4 are great for restoring the immune system and reducing inflammation.
- PT-141 can be used to help with erectile dysfunction. 
- RG3 and VIP are commonly incorporated in the treatment of Lyme and toxic mold syndrome (see my article on mold toxicity for more information on my treatment philosophy).
- LL37 is a potent antimicrobial agent and can be a useful partner in wound healing.
- Pentosan Polysulfate Sodium Peptide (Elmiron) and AOD 9604 decrease pain receptors in the brain, which reduces the subjective perception of pain.
- Melanotan is another peptide with potent anti-inflammatory activity. It targets the vagus nerve via the cholinergic pathway. The result is the removal of inflammatory molecules and calmer brain.
Please consult your health provider before researching or experimenting with ANY peptide or changing your medications. If you have had cancer or have cancer consult your oncologist before even considering peptide research.
Best Day Ever, Bobby
Two Clinical Cases Demonstrating the Healing Effects of Peptides
Dr. Joseph Cleaver gave a talk about two clinical cases demonstrating the healing effects of peptides. His presentation on Dec. 13, 2019 was part of the 27th Annual World Congress on Anti-Aging Medicine. The topic of his talk was “The Power of Peptides – Treatment of End Stage Renal Disease and Congestive Heart Failure, Case Studies “. Dr. Cleaver presented how his 86-year old father who had end stage kidney disease was able to go home from a palliative care facility following peptide treatment.
Next he presented another case of a 51-old man who had sustained a viral cardiomyopathy 7 years earlier. His cardiac condition had recently deteriorated, and his physicians put him on an urgent heart transplant list. After only 3 weeks of the peptide therapy he was taken off the heart transplant list as his condition had improved so much.
The medical team
Both patients received initial treatment by a conventional medical team. In the case of the 86-year old man treatment consisted of draining fluid from both lung areas and doing dialysis for chronic kidney failure. Otherwise the family received the sad news that nothing more was available to help, and he was discharged to the palliative care unit. Similarly, the 51-year old man with an end stage heart condition received conventional treatment and learned that the only other possibility to help him was a heart transplant.
The integrative medicine team that treated both patients later consisted of Dr. Mark Houston, an integrative cardiologist. In addition, there was Dr. Joseph Cleaver, one of the leaders in peptide therapy. The third person was Dr. Andrew Heyman, an expert in integrative medicine.
An 86-year old patient with end-stage kidney failure
Dr. Cleaver said that in May 2019 he received a phone call from the emergency room doctor of the hospital. He said that his father was admitted with serious heart problems and was deteriorating rapidly. He had a history of a multiple myeloma with abnormal deposits called amyloidosis. This material formed deposits in his brain and his heart muscle. As a result, he had developed a weakening of the heart resulting in fluid collection in his lungs. Just recently, on April 3, 2019 two stents were placed in his coronary arteries because of hardening of the heart vessels. He also had chronic renal failure with a very low glomerular filtration rate (GFR), which is a measure of the severity of the condition. The GFR was only 15 meaning that he needed 5 dialysis treatments per week to keep him alive.
Findings in the emergency department
An echocardiogram of the heart confirmed amyloidosis of his heart. He had an effusion around the heart, called pericardial effusion. He also had pleural effusions in both lungs. A further test confirmed kidney failure. He needed daily dialysis treatments to combat the kidney failure. The physicians removed 1600 ml of fluid from both lung cavities. Drug therapy was started to improve his heart failure. He required antibiotics for the beginning of blood poisoning (sepsis). By mid-June he had stabilized and his treatment team sent him to palliative care. The purpose of the transfer was to have another medical team look after him for end of life care.
Dr. Cleaver consulted with his integrative medicine collogues to discuss options of integrative medicine treatment of his father.
Integrative medicine approach to treat kidney failure
On June 10, 2019 the integrative medicine specialists ordered to start therapy with the peptide TB4. TB4 stands for thymosin beta 4. It can reduce infarct size in people with heart attacks. But it can also improve heart muscle function in general.
Another peptide was started on June 10, 2019, namely BPC-157. The doctors ordered this to repair organ damage.
He also received general nutraceutical supplements including the mitochondrial antioxidant MitoQuinol.
Results of integrative treatment
Dr. Cleaver’s father was able to return home in August 2019. His grip strength, gait and general strength were the best he has been in years. He returned to wood working (building furniture). He lifts weights and uses an exercise bike every day. His chronic lower back pain has mostly disappeared. His gait is strong and his balance has improved. He maintains his kidney function with only one dialysis treatment per week. He is looking after his garden, walks without assistance and enjoys spending time with his wife. His heart function has normalized and there is significant improvement in his kidney function.
A 51-old man with viral cardiomyopathy waiting for a heart transplant
The second clinical case that Dr. Cleaver presented was that of a 51-year old man who had contracted a viral cardiomyopathy 7 years earlier. His heart function had slowly deteriorated since then. The doctors had nothing else to offer him with his heart condition except to put him on a waiting list for a heart transplant. His symptoms were shortness of breath and fatigue. In addition he required two pillows for sleeping to cope with his shortness of breath.
Integrative medicine approach to treat heart failure
Here is what the treatment plan from the integrative medicine team for this patient included.
The team concentrated on heart muscle cell regeneration and reconditioning of the cardiac mitochondria. The main peptides used were BPC-157 and thymosin beta 4. Another peptide was Ipamorelin, which is known to release growth hormone. Human growth hormone has been shown to improve heart function in patients with heart failure.
The doctors also ordered CoQ-10 and MitoQuinol to stimulate the mitochondria of the heart muscle. In their search for effective alternative remedies for cardiomyopathy the integrative medicine team found supportive literature. They found that growth hormone releasing hormone and Ipamorelin were stimulating receptors on cardiac stem cells. This stimulates survival of heart muscle fibers and modulates genes that regulate cardiac remodelling. The team also administered Hexarelin and ghrelin, which release growth hormone in the body.
Within only three weeks this patient’s shortness of breath disappeared. His ejection fraction, a measure of left heart chamber contraction normalized. He felt energy and no longer needed two pillows to sleep. Due to his improvement his doctor took him off the heart transplant list.
These two cases demonstrate the limits of conventional medicine. Chronic kidney failure and chronic heart failure are conditions for which the normal health care system has no answers. But interestingly, the integrative medicine team managed using innovative peptides that helped in both of these cases. Dr. Cleaver reminded us that we should not only trust in conventional medicine, particularly when there is no positive result. Integrative medicine can offer alternative approaches for the difficult cases that conventional medicine cannot solve. At this point we do not know all the mechanisms of why peptides are helping. Some papers point out that peptides may stimulate pluripotent stem cells to heal whatever condition it is in the body. Dr. Cleaver provided extensive literature references regarding several peptides that are now in clinical use.
Dr. Cleaver gave a talk about peptides at the 27th Annual World Congress on Anti-Aging Medicine on Dec. 13, 2019. He presented two clinical examples, which could not be dealt with by conventional medicine. The first was an 86-year old patient with end-stage kidney failure. The second was a 51-old man with viral cardiomyopathy waiting for a heart transplant. Miraculously, both cases responded to peptide therapy with TB4 (thymosin beta 4) and BPC157. Within a matter of a few weeks there was clinical improvement in both cases. The 86-year old man could return home from a palliative care home, attend to his garden and do woodworking. The 51-year old man regained his cardiac strength and his physician took him off the heart transplant list. Integrative medicine can be useful in chronic cases that conventional medicine cannot improve.
Peptides are proving to be the cutting edge healing modalities of the 21st century. If you have any question about how you can further your research into peptides please contact me and I will forward more in depth information to you
For all of you guys who are taking hormones and peptides to increase your testosterone and IGF-I, keep in mind researchers have recently found that men with higher concentrations of these two hormones were more likely to be diagnosed with prostate cancer.
For every increase of five nanomoles in the concentration of IGF-I per litre of blood, meant a 9% increase in the likelihood of developing prostate cancer. For every increase of 50 picomoles of ‘free’ testosterone per litre of blood, the studies showed a 10% increase in prostate cancer risk.
The men were followed for an average of six to seven years to see if they went on to develop prostate cancer. Within the group, there were 5,412 cases and 296 deaths from the disease. A subset of 9,000 of men gave a second blood sample at a later date, to help the researchers account for natural fluctuations in hormone levels.
Looking at the population as a whole, the researchers say their findings correspond to a 25% greater risk in men who have the highest levels of IGF-I, compared to those with the lowest. Men with the highest ‘free’ testosterone levels face a 18% greater risk of prostate cancer, compared to those with the lowest levels.
Always check in with your doctor before beginning any hormone or peptide therapies. If you would like more articles on peptides and hormone therapies please comment and let me know.
Blessings, Robert Morgan, ND
National Cancer Research Institute. “High levels of two hormones in the blood raise prostate cancer risk.” ScienceDaily. http://www.sciencedaily.com/releases/2019/10/191031204628.htm (accessed July 2, 2021).
Our bodies naturally makes many chemical compounds that protect our systems and organs. One of the most powerful of these is compounds is our own gastric juices that not only digest our meals, but also serve to protect and heal our gut. BPC-157 is a fragment of a protein found in gastric juice. BPC-157 is formed from these gastric juices and compounded into a peptide that will get it into your system and enable it to go to work identifying, healing and regenerating almost any of the bodies tissues at very fast levels.
What Does it Heal or Repair
Research studies have shown BPC-157 is a repair and heal tendon, muscles, intestines, teeth, bone, arteries and ligaments.
MOTS‐C is found in the mitochondria and is a peptide made of 16 amino acids. MOTS-C is known to control metabolic capacities all through the body. One of the vital components of MOTS-C is transforming glucose into usable energy and holds fat back from gathering in the muscle.
In the event that you are attempting to get more fit, MOTS-C when infused can help support glucose digestion to control glucose levels. MOTS-C is an activity mimetic drug that invigorates changes enacted through exercise and can help improve by and large many aspects of your physical and mental health.
- Helps regulate energy
- Protects against obesity
- Helps with weight loss
- Improves exercise capacity
- Improves glucose regulation
- Improves metabolism
- Helps improve overall health and wellness
Being able to target Breast Cancer cells, with peptides specifically designed to identify and destroy breast cancer cells is beginning to gain a foothold as a highly efficient approach to selectively deliver targeted destruction to cancer cells with minimal cellular toxicity.
Even the highly aggressive form of breast cancer HER2+ is being down regulated by the utilization of peptide enhanced therapies.. The new polymalic acid-based mini nanodrugsare peptides are synthesized and specifically characterized to inhibit growth of HER2+ breast cancer. These mini nanodrugs are highly effective and may soon be able to be substituted for Trastuzumab. The addition of the peptides have caused the HER2+ cells to be recognized, targeted and destroyed by the polymer-attached trastuzumab-mimetic 12-mer peptide at a faster and safer rate than ever, preventing cancer cell proliferation and and causing a significant reduction in tumor size by more than 15 times vs. untreated control group.
Cancer Targeting Peptides – Not to be used on human beings. These Peptides are for research purposes only. I do not have a financial interest in the company or any affiliation. Robert Morgan, ND
There’s been a ton of buzz across the internet about peptides and how they can turn back the hands of time, rejuvenate your skin, rebuild your muscles, help you lose weight and enhance your wellbeing. It would probably be a good idea to know precisely what they are, and at what level will they satisfy our expectations?
What Are Peptides?
Naturally occuring in our foods and our bodies peptides are made up of strings of amino acids, which are the “building blocks” of all proteins.
Today, lab-created peptides can emulate a many of those which are naturally found in foods and our body’s. Over the past few years medical science utilizing peptide meds are beginning to treat:
- ALZHEIMER’S DISEASE
- ANTIMICROBIAL – Bacterial & Viral
- COVID-RELATED PEPTIDES
- HEMATOLOGY -Blood Disease
- MULTIPLE SCLEROSIS
In the next article we will review some of the studies that trackdown that specific kinds benefits peptides may have for your skin, muscles, and perhaps your weight. So, many small and multi-national organizations are incorporating peptides into skin, dietary enhancements as well as food supplements you can purchase over the counter, that we would be remiss if we did not address this powerful segment of health and beauty.
Remember that the FDA doesn’t direct beautifying agents and health enhancements as rigorously as medications. So be alert and use caution when purchasing and utilizing peptide items.
For more info on Peptide Therapy, contact:
Robert Morgan, ND
There’s just something about the summer season that just doesn’t feel quite “summer” without peach cream soda. Now we finally have a healthy version that will not only cool you down, but strengthen your immune system and keep your gut healthy.
Prep Time: 10 mins
Cook Time: 20 mins
- 10 cups peaches sliced
- 3 1/2 cups organic cane sugar
- 14 cups water
- 7 Tbsp vanilla extract
- 1 cup water kefir or kombucha
- Put the peaches, sugar, and water in a large pot and bring to a boil. Reduce to a simmer about 15-20 minutes. Let cool.
- Blend the peaches, and pour them through a fine-mesh strainer into a large bowl.
- Add the vanilla extract and kefir or kombucha to the mixture in the bowl and stir. Once combined, pour into flip top bottles and set in a warm area of your home. I like to put them near the water heater.
- After a couple of days, open a bottle to check for taste and let the fermented gasses out so it doesn’t build up too much. Fermentation can take anywhere from 2 days to a week.
- Make sure you check the bottles daily so you don’t have any explosions. Move the bottles to the fridge once they are ready.
- NOTE: If you have rejuvelac use it instead of water kefir or kombucha.
May your life be filled with every blessings. Dr. Bobby